The Paufique Graft Knife is a specialized ophthalmic surgical instrument widely used in keratoplasty and other advanced corneal transplant procedures. Featuring a 1.6 mm × 1.75 mm angled blade with a sharp, rounded cutting edge, it is designed for the precise dissection of deep corneal stromal tissue while maintaining a plane parallel to Descemet’s membrane. This controlled dissection facilitates the preparation of the cornea for anterior lamellar keratoplasty, helping surgeons achieve accurate tissue separation and optimal graft placement. Engineered for precision, stability, and atraumatic tissue handling, the Paufique Graft Knife is an essential instrument for modern corneal surgery and transplantation procedures.